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Nursing ACNS

ACNS

Exam Code: ACNS

Exam Name: ANCC Adult Health Clinical Nurse Specialist Certification (ACNS)

Updated: Aug 18, 2026

Q & A: 202 Questions and Answers

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Nursing ACNS Exam Syllabus Topics:

SectionObjectives
Topic 1: Systems Leadership and Quality Improvement- Healthcare systems improvement
  • 1. Policy and regulatory compliance
    • 2. Quality and safety initiatives
      Topic 2: Clinical Judgment and Advanced Practice Nursing- Comprehensive health assessment and differential diagnosis
      • 1. Physical assessment across adult populations
        • 2. Clinical reasoning and diagnostic interpretation
          Topic 3: Professional Role Development- Advanced practice nursing roles and ethics
          • 1. Ethical and legal considerations in CNS practice
            • 2. Interprofessional collaboration
              Topic 4: Patient and Family Outcomes Management- Care coordination and chronic disease management
              • 1. Patient education and self-management support
                • 2. Population-focused care strategies
                  Topic 5: Evidence-Based Practice and Research- Translation of research into clinical practice
                  • 1. Critical appraisal of evidence
                    • 2. Implementation of best practices

                      Nursing ANCC Adult Health Clinical Nurse Specialist Certification (ACNS) Sample Questions:

                      1. Your patient has presented in the late stage of Syphilis. Which of the following is the recommended treatment option?

                      A) Benzathine penicillin G 2.4 million U IM x 2 weekly doses.
                      B) Benzathine penicillin G 2.4 million U IM x 3 weekly doses.
                      C) Benzathine penicillin G 2.4 million U IM x 4 weekly doses.
                      D) Benzathine penicillin G 2.4 million U IM as a one-time dose.


                      2. What drug is an example of a Podophyllotoxin?

                      A) Paclitaxel.
                      B) Vinorelbine.
                      C) Etoposide.
                      D) Irinotecan.


                      3. When counseling a patient on side effects of her medication, a question comes up. What is the best way to manage and alleviate a common side effect of trazodone?

                      A) Drink a big glass of water with each dose.
                      B) Eat more fiber while on this medication.
                      C) Take this medication in the morning
                      D) Take this medication at bedtime.


                      4. You have agreed to participate in the Medicare health insurance program and work for a small privately owned physician office. Medicare paid 80% of the charges billed for a clinic visit when the patient was seen by the Adult Clinical Nurse Specialist. What could your employer do about the remaining 20% that is owed to the facility?

                      A) The facility, on behalf of the Adult Clinical Nurse Specialist, can collect 100% if billed incident to the supervision Medical Doctor.
                      B) The facility can resubmit the bill for additional payment on behalf of the Family Clinical Nurse Specialist.
                      C) The facility can bill the patient for a percentage of the remainder on behalf of the Adult Clinical Nurse Specialist.
                      D) The facility is prohibited from billing the patient in this case.


                      5. You are seeing a female patient who has undergone surgery and was bed-bound for a period of time. She has a clinical presentation that is suspicious of deep vein thrombophlebitis (DVT). Which of the following does the Adult Clinical Nurse Specialist find if she has a DVT?

                      A) ecchymosis and joint swelling
                      B) warmth over the affected area
                      C) severe leg pain
                      D) unilateral leg edema


                      Solutions:

                      Question # 1
                      Answer: B
                      Question # 2
                      Answer: C
                      Question # 3
                      Answer: D
                      Question # 4
                      Answer: C
                      Question # 5
                      Answer: D

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